Calendar: Grand Rounds & Lectures
Alfred Hitchcock Presents…
J. A. Bermudez, MD; S. Dubovy, MD; T. Johnson, MD
Mothers, Mummies & Monarchs
D. Gologorsky, MD; J. Davis, MD
Progression Of Metastatic Uveal Melanoma To The Liver
H. Grossniklaus, MD
Jose Berrocal Auditorium
Calendar: McKnight Vision Research Seminars
Markus H. Frank, A.B., M.D.
Assistant Professor of Pediatric and Dermatology
Harvard Medical School Transplant Research Program, Boston Children’s Hospital;
Adjunct Associate Professor, School of Medical Sciences, Edith Cowan University, Perth, Australia; Staff Physician, Bedford VA Medical Center
“Stem Cell-Targeted Approaches to Tissue Regeneration and Cancer”
The ATP-binding cassette member ABCB5 identifies normal tissue-specific stem cells in human limbus and skin, and, when overexpressed in malignant tissues, marks tumor-initiating cells in diverse human cancers. Furthermore, critical functional roles of ABCB5 in stem cell maintenance have recently been discovered. Here, Dr. Frank will discuss the use of ABCB5 and related stem cell molecular pathways in novel stem cell-targeted approaches to tissue regeneration and cancer.