Malignant tumors from other parts of the body can spread in and around the eye. Metastatic cancers that appear in the eye usually come from a primary cancer of the breast in women and the lungs in men. Other, less common, sites of origin include the prostate, kidneys, thyroid, and the gastrointestinal tract. Blood cell tumors (lymphomas and leukemia) also can spread to the eye. The care of patients with metastasis to the eye should be coordinated between the eye cancer specialist, medical oncologist, and radiation oncologist. Treatment options may include chemotherapy, external beam radiation therapy, or, more rarely, enucleation.